Article
IL-23R gene confers susceptibility to Behcet's disease in a Chinese Han population.
Annals of the rheumatic diseases - 1 Jul 2010
Jiang Zhengxuan, Yang Peizeng, Hou Shengping, Du Liping, Xie Lin, Zhou Hongyan, Kijlstra Aize
Abstract excerpt
PURPOSE: IL-23 has been shown to be involved in the pathogenesis of Behcet's disease (BD) through promoting IL-17 production. This study examined whether IL-23R polymorphisms were associated with susceptibility to this disease in a Chinese Han population. METHODS: Four single-nucleotide polymorphisms (SNP), rs7517847, rs11209032, rs 1343151 and rs17375018 were genotyped in 338 BD patients and 407 age, sex and...
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