Article
Interleukin 23 receptor gene polymorphisms and their role in the inflammatory status of rheumatoid arthritis patients in an Iranian population.
International journal of rheumatic diseases - 1 Feb 2023
Abbasifard Mitra, Mirzaei Mohammad Reza, Abade Mahsa, Bagheri-Hosseinabadi Zahra
Abstract excerpt
BACKGROUND: Several investigations have disclosed the involvement of the interleukin (IL)-23/IL-17 pathway in rheumatoid arthritis (RA) pathogenesis. Here we investigated the association of single nucleotide polymorphisms (SNPs) in the IL23 receptor (IL23R) gene with RA risk. In addition, the rol...
Topics
- Humans
- Interleukin-17
- Iran
- Genetic Predisposition to Disease
- Case-Control Studies
- Leukocytes, Mononuclear
- Gene Frequency
- Arthritis, Rheumatoid
- Genotype
- Receptors, Interleukin
- Polymorphism, Single Nucleotide
- Interleukin-23