Article
Interleukin 23 receptor gene polymorphisms and their role in the inflammatory status of rheumatoid arthritis patients in an Iranian population.
International journal of rheumatic diseases - 1 Feb 2023
Abbasifard Mitra, Mirzaei Mohammad Reza, Abade Mahsa, Bagheri-Hosseinabadi Zahra
Abstract excerpt
BACKGROUND: Several investigations have disclosed the involvement of the interleukin (IL)-23/IL-17 pathway in rheumatoid arthritis (RA) pathogenesis. Here we investigated the association of single nucleotide polymorphisms (SNPs) in the IL23 receptor (IL23R) gene with RA risk. In addition, the role of these SNPs with the inflammatory state of the patients were determined. METHODS: In this case-control study, 200...
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