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Article

Association of genetic polymorphisms in IL-23R and IL-17A with the susceptibility to IgA nephropathy in a Chinese Han population.

Genes and immunity - 1 Feb 2022

Liao Hongyan, Huang Zhuochun, Zhang Junlong, Yang Bin

Abstract excerpt

IgA Nephropathy (IgAN) is one of the most common causes of chronic kidney damage worldwide. Identifying new genetic factors associated with IgAN risk is of invaluable importance. To explore the association between polymorphisms of IL-23R and IL-17A and the susceptibility of IgAN, 164 IgAN patients and 192 healthy controls were genotyped for five SNPs in a Chinese Han population. A comparative analysis between...

Topics

Case-Control Studies
China
Female
Genetic Predisposition to Disease
Genotype
Glomerulonephritis, IGA
Humans
Interleukin-17
Male
Polymorphism, Single Nucleotide
Receptors, Interleukin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34952933
DOI: 10.1038/s41435-021-00160-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-34952933-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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