Article
Association between polymorphisms of the IL-23R gene and allergic rhinitis in a Chinese Han population.
PloS one - 1 Jan 2013
Hu Di, Hu Guohua, Zhu Jing, Shen Yang, Kang Houyong, Hong Suling
Abstract excerpt
OBJECTIVE: Polymorphism of the interleukin-23 receptor gene corresponds with susceptibility to several immune-related diseases. For the terminal differentiation of IL-17-producing effector T-helper cells in vivo, the interleukin-23 receptor gene is of vital importance. As shown recently, Th17 cells probably have a great influence on the pathogenesis of allergic airway diseases. Our intention was to establish an...
Topics
- Adult
- Asian People
- Female
- Genetic Predisposition to Disease
- Humans
- Male
- Middle Aged
- Polymorphism, Genetic
- Receptors, Interleukin
- Rhinitis, Allergic
- Rhinitis, Allergic, Perennial
