IFNL4 ss469415590 polymorphism is associated with unfavourable clinical and immunological status in HIV-infected individuals.

doi:10.1016/j.cmi.2014.10.012

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Article

IFNL4 ss469415590 polymorphism is associated with unfavourable clinical and immunological status in HIV-infected individuals.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Mar 2015

Machmach K, Abad-Molina C, Romero-Sánchez M C, Dominguez-Molina B, Moyano M, Rodriguez M M, Rafii-El-Idrissi Benhnia M, Jimenez-Mejias M E, Vidal F, Muñoz-Fernández M A, Genebat M, Viciana P, González-Escribano M F, Leal M, Ruiz-Mateos E

Abstract excerpt

The IFNL4 ss469415590 polymorphism, in high linkage disequilibrium with the IL28B rs12979860 variant, has been associated with hepatitis C virus clearance. We evaluated whether ss469415590 is associated with clinical and immunovirological parameters in human immunodeficiency virus-infected subjects. We found an independent association of the IFNL4 ss469415590 polymorphism with higher prevalence of AIDS-defining...

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PMID: 25658540
DOI: 10.1016/j.cmi.2014.10.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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