Article
The novel ss469415590 variant predicts virological response to therapy in patients with chronic hepatitis C virus type 1 infection.
Alimentary pharmacology & therapeutics - 1 Feb 2014
Covolo L, Bibert S, Donato F, Bochud P-Y, Lagging M, Negro F, Fattovich G
Abstract excerpt
BACKGROUND: A novel dinucleotide variant TT/∆G (ss469415590) has been associated with hepatitis C virus clearance. AIM: To assess the role of the ss469415590 variant, compared with the known IL28B polymorphisms (rs8099917, rs12979860 and rs12980275) for predicting virological response to therapy in chronic hepatitis C, and its association with the CXCL10 chemokine serum levels - a surrogate marker of...
Read the complete abstract on PubMed