Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IFNL4 genotype influences the rate of HIV-1 seroconversion in men who have sex with men.

Virulence - 1 Dec 2022

Meza Giovanna, Galián Fátima, Jaimes-Bernal Claudia, Márquez Francisco J, Sinangil Faruk, Scagnolari Carolina, Real Luis Miguel, Forthal Donald, Caruz Antonio

Abstract excerpt

Individuals lacking interferon lambda 4 (IFNL4) protein due to a common null mutation (rs368234815) in the IFNL4 gene display higher resistance against several infections. The influence of IFNL4 on HIV-1 infection is still under discussion and conflicting results have been reported. This study intended to corroborate or refute the association of the null allele of IFNL4 and HIV-1 predisposition in a cohort of men...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Homosexuality, Male

Share to Interferons

Share to Interleukins

Share to Sexual and Gender Minorities

Source

Open in PubMed Open full text

Identifiers

PMID: 35481423
DOI: 10.1080/21505594.2022.2066612
PMCID: PMC9067526

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IFNL4 genotype influences the rate of HIV-1 seroconversion in men who have sex with men.PMID 35481423Read ↗

IFNL4 rs368234815 polymorphism is associated with innate resistance to HIV-1 infection.Semantic proximity Read ↗

Interferon lambda rs368234815 ΔG/ΔG is associated with higher CD4+:CD8+ T-cell ratio in treated HIV-1 infection.Semantic proximity Read ↗

No Association of IFNL4 Genotype With Opportunistic Infections and Cancers Among Men With Human Immunodeficiency Virus 1 Infection.Semantic proximity Read ↗

Targeted next-generation sequencing approach for CCR5, CXCR4 and IFNAR1 genes in HIV+ participants: Association of single nucleotide polymorphisms with CD4+ T cell count and HIV replication in patients receiving antiretroviral therapySemantic proximity Read ↗

IFNL4: Notable variants and associated phenotypes.Semantic proximity Read ↗

The Impact of IFNλ4 on the Adaptive Immune Response to SARS-CoV-2 Infection.Semantic proximity Read ↗

Interferon Lambda 4 Genotype Is Not Associated with Recurrence of Oral or Genital Herpes.Semantic proximity Read ↗

IFN-stimulated gene expression is independent of the IFNL4 genotype in chronic HIV-1 infection.Semantic proximity Read ↗

Association of the IFNL4-ΔG Allele With Impaired Spontaneous Clearance of Hepatitis C Virus.Semantic proximity Read ↗

Association between variants in the interferon lambda 4 locus and substitutions in the hepatitis C virus non-structural protein 5A.Semantic proximity Read ↗

Multiple Homozygous Variants in the STING-Encoding TMEM173 Gene in HIV Long-Term Nonprogressors.Semantic proximity Read ↗

Variants of IFNL4 Gene in Amazonian and Northern Brazilian Populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.