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Article

Prognostic value of MGMT promoter methylation and TP53 mutation in glioblastomas depends on IDH1 mutation.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Wang Kai, Wang Yin-Yan, Ma Jun, Wang Jiang-Fei, Li Shao-Wu, Jiang Tao, Dai Jian-Ping

Abstract excerpt

Several molecular markers have been proposed as predictors of outcome in patients with glioblastomas. We investigated the prognostic significance of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and TP53 mutation status dependent on isocitrate dehydrogenase 1 (IDH1) mutation in glioblastoma patients. A cohort of 78 patients with histologically confirmed glioblastomas treated with radiation...

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Source

Identifiers

PMID: 25605197
DOI: 10.7314/apjcp.2014.15.24.10893

Genes

IDH1
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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