Article
Prognostic significance of IDH 1 mutation in patients with glioblastoma multiforme.
JPMA. The Journal of the Pakistan Medical Association - 1 May 2017
Khan Inamullah, Waqas Muhammad, Shamim Muhammad Shahzad
Abstract excerpt
Focus of brain tumour research is shifting towards tumour genesis and genetics, and possible development of individualized treatment plans. Genetic analysis shows recurrent mutation in isocitrate dehydrogenase (IDH1) gene in most Glioblastoma multiforme (GBM) cells. In this review we evaluated the prognostic significance of IDH 1 mutation on the basis of published evidence. Multiple retrospective clinical...
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