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Article

IDH mutation and MGMT promoter methylation in glioblastoma: results of a prospective registry.

Oncotarget - 1 Dec 2015

Yang Pei, Zhang Wei, Wang Yinyan, Peng Xiaoxia, Chen Baoshi, Qiu Xiaoguang, Li Guilin, Li Shouwei, Wu Chenxing, Yao Kun, Li Wenbin, Yan Wei, Li Jie, You Yongping, Chen Clark C, Jiang Tao

Abstract excerpt

BACKGROUND: The relative contribution of isocitrate dehydrogenase mutations (mIDH) and O6-methylguanine-DNA methyltransferase promoter methylation (methMGMT) as biomarkers in glioblastoma remain poorly understood. METHODS: We investigated the association between methMGMT and mIDH with progression free survival and overall survival in a prospectively collected molecular registry of 274 glioblastoma patients....

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Source

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Identifiers

PMID: 26503470
DOI: 10.18632/oncotarget.5683
PMCID: PMC4747376

Genes

MGMT
IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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