Article

Clinical Impact of IDH1 Mutations and MGMT Methylation in Adult Glioblastoma

2022-05-13

Abstract excerpt

<h4>Background: </h4> Genetic aberrations and epigenetic alterations have been reported in different types of cancer. Impact of Isocitrate dehydrogenase1 ( IDH1 ) and O6-methylguanine-DNAmethyltransferase ( MGMT ) in glioblastoma (GB) have been of great interest due to their implications in prediction of prognosis of several types of cancer. It was aimed to investigate the clinical role of IDH1 mutation and MGMT m...

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Literature Corpus work: fcbdb6f0-0d08-50d3-9427-4d24affa6b47
DOI: 10.21203/rs.3.rs-1623723/v1

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