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Article

IDH1/IDH2 mutations define the prognosis and molecular profiles of patients with gliomas: a meta-analysis.

PloS one - 1 Jan 2013

Zou Peng, Xu Haitao, Chen Pin, Yan Qing, Zhao Lin, Zhao Peng, Gu Aihua

Abstract excerpt

BACKGROUND: Isocitrate dehydrogenase isoforms 1 and 2 (IDH1 and IDH2) mutations have received considerable attention since the discovery of their relation with human gliomas. The predictive value of IDH1 and IDH2 mutations in gliomas remains controversial. Here, we present the results of a meta-analysis of the associations between IDH mutations and both progression-free survival (PFS) and overall survival (OS) in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 23894344
DOI: 10.1371/journal.pone.0068782
PMCID: PMC3718803

Genes

IDH1
IDH2
EGFR
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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