Article

Clinical Impact of <i>IDH1</i> Mutations and <i>MGMT</i> Methylation in Adult Glioblastoma Multiforme

2022-04-07

Abstract excerpt

<h4>Background</h4> Genetic aberrations and epigenetic alterations have been reported in different types of cancer. Impact of Isocitrate dehydrogenase1 ( IDH1 ) and O6-methylguanine-DNAmethyltransferase ( MGMT ) in glioblastoma multiforme (GBM) have been of great interest due to their implications in prediction of prognosis of several types of cancer. Authors aimed to investigate the clinical role of IDH1 mutation...

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Literature Corpus work: a64f8b37-4d18-5c3f-808c-11afba774401
DOI: 10.1101/2022.03.30.22273163

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