Article
A mutational and expressional analysis of DNMT3A in acute myeloid leukemia cytogenetic subgroups.
Hematology (Amsterdam, Netherlands) - 1 Aug 2015
Zare-Abdollahi Davood, Safari Shamsi, Movafagh Abolfazl, Riazi-Isfahani Sahand, Ghadyani Mojtaba, Hashemi-Gorji Feyzollah, Feyzollah Hashemi-Gorji, Nasrollahi Mohammad Foad, Omrani Mir Davood
Abstract excerpt
OBJECTIVES: Despite numerous studies in order to determine the allele frequency and clinical impact of DNA methyltransferase 3 A (DNMT3A) gene mutations in acute myeloid leukemia (AML), reports about the expression analysis of this gene are rare and between the available, differences are evident. METHODS: In this study, we decided to investigate DNMT3A possible expression changes with regard to their mutation and...
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