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Article

Common variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program.

Diabetologia - 1 Mar 2014

Franks Paul W, Christophi Costas A, Jablonski Kathleen A, Billings Liana K, Delahanty Linda M, Horton Edward S, Knowler William C, Florez Jose C

Abstract excerpt

AIMS/HYPOTHESIS: PPARGC1A and PPARGCB encode transcriptional coactivators that regulate numerous metabolic processes. We tested associations and treatment (i.e. metformin or lifestyle modification) interactions with metabolic traits in the Diabetes Prevention Program, a randomised controlled trial in persons at high risk of type 2 diabetes. METHODS: We used Tagger software to select 75 PPARGCA1 and 94 PPARGC1B...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha

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Source

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Identifiers

PMID: 24317794
DOI: 10.1007/s00125-013-3133-4
PMCID: PMC4154629

Genes

PPARGC1A
PPARGC1B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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