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Article

SNPs in PPARG associate with type 2 diabetes and interact with physical activity.

Medicine and science in sports and exercise - 1 Jan 2008

Kilpeläinen Tuomas O, Lakka Timo A, Laaksonen David E, Lindström Jaana, Eriksson Johan G, Valle Timo T, Hämäläinen Helena, Ilanne-Parikka Pirjo, Keinänen-Kiukaanniemi Sirkka, Lindi Virpi, Tuomilehto Jaakko, Uusitupa Matti, Laakso Markku

Abstract excerpt

PURPOSE: To study the associations of seven single-nucleotide polymorphisms (SNPs) in the peroxisome proliferator-activated receptor gamma (PPARG) gene with the conversion from impaired glucose tolerance (IGT) to type 2 diabetes (T2D), and the interactions of the SNPs with physical activity (PA). METHODS: Overweight individuals with IGT who participated in the Finnish Diabetes Prevention Study (DPS) (N = 479)...

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Identifiers

PMID: 18091023
DOI: 10.1249/mss.0b013e318159d1cd

Genes

PPARG

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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