Article
The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences.
Diabetes - 1 Apr 2001
Douglas J A, Erdos M R, Watanabe R M, Braun A, Johnston C L, Oeth P, Mohlke K L, Valle T T, Ehnholm C, Buchanan T A, Bergman R N, Collins F S, Boehnke M, Tuomilehto J
Abstract excerpt
Recent studies have identified a common proline-to-alanine substitution (Pro12Ala) in the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2), a nuclear receptor that regulates adipocyte differentiation and possibly insulin sensitivity. The Pro12Ala variant has been associated in some studies with diabetes-related traits and/or protection against type 2 diabetes. We examined this variant in 935...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.