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Article

Endothelial protein C receptor gene variants not associated with severe malaria in ghanaian children.

PloS one - 1 Jan 2014

Schuldt Kathrin, Ehmen Christa, Evans Jennifer, May Juergen, Ansong Daniel, Sievertsen Juergen, Muntau Birgit, Ruge Gerd, Agbenyega Tsiri, Horstmann Rolf D

Abstract excerpt

BACKGROUND: Two recent reports have identified the Endothelial Protein C Receptor (EPCR) as a key molecule implicated in severe malaria pathology. First, it was shown that EPCR in the human microvasculature mediates sequestration of Plasmodium falciparum-infected erythrocytes. Second, microvascular thrombosis, one of the major processes causing cerebral malaria, was linked to a reduction in EPCR expression in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25541704
DOI: 10.1371/journal.pone.0115770
PMCID: PMC4277309

Genes

PROCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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