Article
Human genetic polymorphisms in the Knops blood group are not associated with a protective advantage against Plasmodium falciparum malaria in Southern Ghana.
Malaria journal - 7 Nov 2013
Hansson Helle H, Kurtzhals Jørgen A, Goka Bamenla Q, Rodriques Onike P, Nkrumah Francis N, Theander Thor G, Bygbjerg Ib Christian, Alifrangis Michael
Abstract excerpt
BACKGROUND: The complex interactions between the human host and the Plasmodium falciparum parasite and the factors influencing severity of disease are still not fully understood. Human single nucleotide polymorphisms SNPs associated with Knops blood group system; carried by complement receptor 1 may be associated with the pathology of P. falciparum malaria, and susceptibility to disease. METHODS: The objective of...
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