Article
Polymorphisms in the RNASE3 gene are associated with susceptibility to cerebral malaria in Ghanaian children.
PloS one - 1 Jan 2011
Adu Bright, Dodoo Daniel, Adukpo Selorme, Gyan Ben A, Hedley Paula L, Goka Bamenla, Adjei George O, Larsen Severin O, Christiansen Michael, Theisen Michael
Abstract excerpt
BACKGROUND: Cerebral malaria (CM) is the most severe outcome of Plasmodium falciparum infection and a major cause of death in children from 2 to 4 years of age. A hospital based study in Ghana showed that P. falciparum induces eosinophilia and found a significantly higher serum level of eosinophil cationic protein (ECP) in CM patients than in uncomplicated malaria (UM) and severe malaria anemia (SA) patients....
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