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Article

A functional single-nucleotide polymorphism in the CR1 promoter region contributes to protection against cerebral malaria.

The Journal of infectious diseases - 15 Dec 2008

Teeranaipong Phairote, Ohashi Jun, Patarapotikul Jintana, Kimura Ryosuke, Nuchnoi Pornlada, Hananantachai Hathairad, Naka Izumi, Putaporntip Chaturong, Jongwutiwes Somchai, Tokunaga Katsushi

Abstract excerpt

BACKGROUND: Although the level of erythrocyte complement receptor type 1 (E-CR1) expression in patients with malaria has been extensively studied, whether the level of expression of E-CR1 is associated with severe malaria remains controversial. The present study examined a possible association of polymorphisms in the CR1 gene with the severity of malaria, and it evaluated the influence of the associated...

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Share to Complement system in diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Malaria, Cerebral

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Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to Receptors, Complement 3b

Source

Identifiers

PMID: 18954261
DOI: 10.1086/593338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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