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Article

Triggering receptor expressed on myeloid cells 1 (TREM-1) and cytokine gene variants in complicated and uncomplicated malaria.

Tropical medicine & international health : TM & IH - 1 Dec 2016

Adukpo Selorme, Gyan Ben A, Ofori Michael F, Dodoo Daniel, Velavan Thirumalaisamy P, Meyer Christian G

Abstract excerpt

BACKGROUND: Malaria elicits inflammatory responses, which, if not well regulated, may exert detrimental effects. When activated, triggering receptor expressed on myeloid cells 1 (TREM-1) enhances inflammatory responses by increasing secretion of IL-8 and other Th1 cytokines. In contrast, TREM-like transcript 1 (TREML-1) promotes anti-inflammatory responses by binding to TREM-1 ligands and competing with TREM-1,...

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Identifiers

PMID: 27671831
DOI: 10.1111/tmi.12787

Genes

TREM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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