Article
Lack of Association of CD55 Receptor Genetic Variants and Severe Malaria in Ghanaian Children.
G3 (Bethesda, Md.) - 10 Mar 2017
Schuldt Kathrin, Ehmen Christa, Sievertsen Juergen, Evans Jennifer, May Juergen, Ansong Daniel, Muntau Birgit, Ruge Gerd, Timmann Christian, Agbenyega Tsiri, Horstmann Rolf D, Thye Thorsten
Abstract excerpt
In a recent report, the cellular receptor CD55 was identified as a molecule essential for the invasion of human erythrocytes by Plasmodium falciparum, the causal agent of the most severe form of malaria. As this invasion process represents a critical step during infection with the parasite, it was hypothesized that genetic variants in the gene could affect severe malaria (SM) susceptibility. We performed...
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