Article
The Functional Copy Number Variation-67048 in WWOX Contributes to Increased Risk of COPD in Southern and Eastern Chinese.
COPD - 1 Jan 2015
Yang Lei, Qiu Fuman, Fang Wenxiang, Zhang Lisha, Xie Chenli, Lu Xiaoxiao, Huang Dongsheng, Guo Yuan, Pan Mingan, Zhang Haibo, Zhou Yifeng, Lu Jiachun
Abstract excerpt
Recent studies have recognized the genetic variants in the WW domain-containing oxidoreductase (WWOX) gene as genetic determinants of lung function, reflecting that the WWOX gene may be a susceptible factor of chronic obstructive pulmonary disease (COPD), which characters as poor lung function. We have previously showed that the copy number variation-67048 (CNV-67048) of WWOX was associated with lung cancer risk....
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