Article
Duplicated copy of CHRNA7 increases risk and worsens prognosis of COPD and lung cancer.
European journal of human genetics : EJHG - 1 Aug 2015
Yang Lei, Lu Xiaoxiao, Qiu Fuman, Fang Wenxiang, Zhang Lisha, Huang Dongsheng, Xie Chenli, Zhong Nanshan, Ran Pixin, Zhou Yifeng, Lu Jiachun
Abstract excerpt
Recent genome-wide association studies implicated that the nicotinic acetylcholine receptors (nAChRs) are common susceptible genes of two contextual diseases: chronic obstructive pulmonary disease (COPD) and lung cancer. We aimed to test whether the copy number variations (CNVs) in nAChRs have he...
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