Article
The polymorphisms and haplotypes of WWOX gene are associated with the risk of lung cancer in southern and eastern Chinese populations.
Molecular carcinogenesis - 1 Nov 2013
Huang Dongsheng, Qiu Fuman, Yang Lei, Li Yinyan, Cheng Mei, Wang Hui, Ma Guanpei, Wang Yunnan, Hu Min, Ji Weidong, Zhou Yifeng, Lu Jiachun
Abstract excerpt
The WW domain-containing oxidoreductase (WWOX) gene is an identified tumor suppressor gene, of which several single nucleotide polymorphisms have been reported to contribute to cancer susceptibility. We hypothesized that genetic variations in WWOX are associated with lung cancer risk. In two independent case-control studies conducted in southern and eastern Chinese, we genotyped five tagSNPs of WWOX gene...
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