Article
Association study of a functional copy number variation in the WWOX gene with risk of gliomas among Chinese people.
International journal of cancer - 1 Oct 2014
Yu Ke, Fan Jin, Ding Xin, Li CongYang, Wang Jun, Xiang Yang, Wang Qing Song
Abstract excerpt
Gliomas represents more than 80% of all malignant brain tumors. However, the etiology still remains largely unknown. Human WW domain-containing oxidoreductase (WWOX), which is located at 16q23.1-16q23.2, the common fragile site 16D (FRA16D), an area with a high frequency of gene deletions or chromosomal alterations, has been identified as a tumor suppressor gene in multiple cancers. In current study, we analyzed...
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