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Article

WWOX gene may contribute to progression of non-small-cell lung cancer (NSCLC).

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2010

Baykara Onur, Demirkaya Ahmet, Kaynak Kamil, Tanju Serhan, Toker Alper, Buyru Nur

Abstract excerpt

Lung cancer is the most common cause of cancer-related death worldwide and, like many other cancers, is affected by different genetic, epigenetic, and environmental factors. The WW domain-containing oxidoreductase (WWOX) gene is a tumor-suppressor gene located on chromosome 16q23.3-24.1, and it has been shown that it loses its function due to alterations in genetic and epigenetic mechanisms. The aim of this study...

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Source

Identifiers

PMID: 20480411
DOI: 10.1007/s13277-010-0039-3

Genes

WWOX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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WWOX gene may contribute to progression of non-small-cell lung cancer (NSCLC).PMID 20480411Read ↗

The polymorphisms and haplotypes of WWOX gene are associated with the risk of lung cancer in southern and eastern Chinese populations.Semantic proximity Read ↗

Effect of WW Domain-Containing Oxidoreductase Gene Polymorphism on Clinicopathological Characteristics of Patients with EGFR Mutant Lung Adenocarcinoma in Taiwan.Semantic proximity Read ↗

A functional copy number variation in the WWOX gene is associated with lung cancer risk in Chinese.Semantic proximity Read ↗

Functional genetic variant in the Kozak sequence of WW domain-containing oxidoreductase (WWOX) gene is associated with oral cancer risk.Semantic proximity Read ↗

WWOX in biological control and tumorigenesisSemantic proximity Read ↗

The Functional Copy Number Variation-67048 in WWOX Contributes to Increased Risk of COPD in Southern and Eastern Chinese.Semantic proximity Read ↗

Relationship of genetic variant distributions of WW domain-containing oxidoreductase gene with uterine cervical cancer.Semantic proximity Read ↗

Genetic and epigenetic alterations of WWOX in the development of gastric cardia adenocarcinoma.Semantic proximity Read ↗

The role of WWOX polymorphisms on COPD susceptibility and pulmonary function traits in Chinese: a case-control study and family-based analysis.Semantic proximity Read ↗

Functional genetic variant of WW domain-containing oxidoreductase (WWOX) gene is associated with hepatocellular carcinoma risk.Semantic proximity Read ↗

Targeted deletion of Wwox reveals a tumor suppressor function.Semantic proximity Read ↗

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer.Semantic proximity Read ↗

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