Article
Genome-Wide Association Analysis of Rapid Decline in Lung Function: Analysis From the Korean Genome and Epidemiology Study.
Journal of Korean medical science - 4 Nov 2024
Kim Sang Hyuk, Lee Hyun, Jo Yong Suk, Yoo Jaeeun, Choi Joon Young
Abstract excerpt
BACKGROUND: A rapid decline in forced expiratory volume in 1 second (FEV1) is considered an important phenotype of the development of chronic obstructive pulmonary disease (COPD). However, the associations between specific genetic variants (single-nucleotide polymorphisms; SNPs) and this phenotype remain uncertain. METHODS: We enrolled 6,516 individuals from the Korean Genome and Epidemiology Study (KoGES). A...
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