Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A functional CNVR_3425.1 damping lincRNA FENDRR increases lifetime risk of lung cancer and COPD in Chinese.

Carcinogenesis - 8 Mar 2018

Yang Lei, Wu Di, Chen Jinbin, Chen Jiansong, Qiu Fuman, Li Yinyan, Liu Li, Cao Yi, Yang Binyao, Zhou Yifeng, Lu Jiachun

Abstract excerpt

Genomic imbalance referring to somatic variation in chromosome copies represents the most frequent event in tumorigenesis. Germline copy number variations (gCNVs) overlapping regions of genomic imbalance harbor similar structural characteristics and thus influence tumor susceptibility. We aimed to test effects of such gCNVs on the risk of lung cancer and chronic obstructive pulmonary disease (COPD). Genomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Copy Number Variations
Share to Forkhead Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Heterografts

Share to Lung Neoplasms

Share to Mice, Inbred BALB C

Share to Pulmonary Disease, Chronic Obstructive

Share to RNA, Long Noncoding

Source

Identifiers

PMID: 29293945
DOI: 10.1093/carcin/bgx149

Genes

FOXF1
EGR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A functional CNVR_3425.1 damping lincRNA FENDRR increases lifetime risk of lung cancer and COPD in Chinese.PMID 29293945Read ↗

Association of nsv823469 copy number loss with decreased risk of chronic obstructive pulmonary disease and pulmonary function in Chinese.Semantic proximity Read ↗

Screening of lung cancer related SNPs and CNVs with SNP microarrays.Semantic proximity Read ↗

Large-scale association study identifies lung cancer susceptibility copy number variants and their potential functional role in genetic instabilitySemantic proximity Read ↗

Genome-wide association study of copy number variations associated with pulmonary function measures in Korea Associated Resource (KARE) cohorts.Semantic proximity Read ↗

The Functional Copy Number Variation-67048 in WWOX Contributes to Increased Risk of COPD in Southern and Eastern Chinese.Semantic proximity Read ↗

Targeted next-generation sequencing for cancer-associated gene mutation and copy number detection in 206 patients with non-small-cell lung cancer.Semantic proximity Read ↗

Strong evidence for LncRNA ZNRD1-AS1, and its functional Cis- eQTL locus contributing more to the susceptibility of lung cancer.Semantic proximity Read ↗

Characterization of germline mutations in familial lung cancer from the Chinese population.Semantic proximity Read ↗

Copy number variation at 6q13 is associated with lung cancer risk in a Han Chinese population.Semantic proximity Read ↗

Polymorphisms and rare variants identified by next-generation sequencing confer risk for lung cancer in han Chinese population.Semantic proximity Read ↗

Identification of regulatory SNPs associated with genetic modifications in lung adenocarcinoma.Semantic proximity Read ↗

rs66651343 and rs12909095 confer lung cancer risk by regulating CCNDBP1 expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.