Article
The role of WWOX polymorphisms on COPD susceptibility and pulmonary function traits in Chinese: a case-control study and family-based analysis.
Scientific reports - 23 Feb 2016
Xie Chenli, Chen Xiaoliang, Qiu Fuman, Zhang Lisha, Wu Di, Chen Jiansong, Yang Lei, Lu Jiachun
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in the WW domain containing oxidoreductase (WWOX) gene were recently identified to be quantitative trait loci for lung function and thus likely to be susceptible biomarkers for COPD. However, the associations between WWOX SNPs and COPD risk are still unclear. Here, by conducting a two-center case-control study including 1511 COPD cases and 1677 controls and a family-based...
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