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Article

Association of nsv823469 copy number loss with decreased risk of chronic obstructive pulmonary disease and pulmonary function in Chinese.

Scientific reports - 12 Jan 2017

Chen Xiaoliang, Lu Xiaoxiao, Chen Jiansong, Wu Di, Qiu Fuman, Xiong Huali, Pan Zihua, Yang Lei, Yang Binyao, Xie Chenli, Zhou Yifeng, Huang Dongsheng, Zhou Yumin, Lu Jiachun

Abstract excerpt

It is highly possible that copy number variations (CNVs) in susceptible regions have effects on chronic obstructive pulmonary disease (COPD) development, while long noncoding RNA (lncRNAs) have been shown to cause COPD. We hypothesized that the common CNV, named nsv823469 located on 6p22.1, and covering lncRNAs (major histocompatibility complex, class I, A (HLA-A) and HLA complex group 4B (HCG4B)) has an effect...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28079130
DOI: 10.1038/srep40060
PMCID: PMC5227687

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