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Article

Genetic variant in the 3'-untranslated region of VEGFR1 gene influences chronic obstructive pulmonary disease and lung cancer development in Chinese population.

Mutagenesis - 1 Sept 2014

Wang Hui, Yang Lei, Deng Jieqiong, Wang Bo, Yang Xiaorong, Yang Rongrong, Cheng Mei, Fang Wenxiang, Qiu Fuman, Zhang Xin, Ji Weidong, Ran Pixin, Zhou Yifeng, Lu Jiachun

Abstract excerpt

Lung inflammation and epithelial to mesenchymal transition (EMT) are two pathogenic features for the two contextual diseases: chronic obstructive pulmonary disease (COPD) and lung cancer. VEGFR1 (or FLT1) plays a certain role in promoting tumour growth, inflammation and EMT. To simultaneously test the association between the single nucleotide polymorphisms (SNPs) in VEGFR1 and risk of COPD and lung cancer would...

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Identifiers

PMID: 24891316
DOI: 10.1093/mutage/geu020

Genes

FLT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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