Article
The variant rs8048002 T>C in intron 3 of the MHC2TA gene is associated with risk of developing acute coronary syndrome.
Cytokine - 1 Feb 2015
Vargas-Alarcón Gilberto, Posadas-Romero Carlos, Posadas-Sánchez Rosalinda, Martínez-Alvarado Roció, González-Pacheco Héctor, Martínez-Sánchez Carlos, Martínez-Ríos Marco Antonio, Juarez-Cedillo Teresa, Ramirez-Fuentes Silvestre, Pérez-Méndez Oscar, Fragoso José Manuel
Abstract excerpt
Recently, an intronic single nucleotide polymorphism (rs8048002) in the MHC class II transactivator gene (MHC2TA) was shown to be associated with increased susceptibility to several inflammatory diseases. The aim of the present study was to test for an association between this MHC2TA gene polymorphism and susceptibility to the risk of developing acute coronary syndromes (ACS) in a group of Mexicans patients. The...
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