Article
Alleles and haplotypes of the interleukin 10 gene polymorphisms are associated with risk of developing acute coronary syndrome in Mexican patients.
Cytokine - 1 Jul 2011
Fragoso José Manuel, Vallejo Maite, Alvarez-León Edith, Delgadillo Hilda, Peña-Duque Marco Antonio, Cardoso-Saldaña Guillermo, Posadas-Romero Carlos, Martínez-Ríos Marco Antonio, Vargas-Alarcón Gilberto
Abstract excerpt
Inflammation plays an important role in the pathogenesis of atherosclerosis and acute coronary syndromes (ACS). Interleukin-10 (IL-10) is a potent anti-inflammatory cytokine that mediates the inflammatory process. The objective of the present study was to evaluate the role of IL-10 gene polymorphisms as susceptibility markers for ACS in Mexican patients. IL-10 promoter polymorphisms (positions -1082, -819, and...
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