Article
Association of the -1031T>C polymorphism and soluble TNF-α levels with Acute Coronary Syndrome.
Cytokine - 1 Feb 2016
Sandoval-Pinto Elena, Padilla-Gutiérrez Jorge Ramón, Valdés-Alvarado Emmanuel, García-González Ilian Janet, Valdez-Haro Angélica, Muñoz-Valle José Francisco, Flores-Salinas Hector Enrique, Brennan-Bourdon Lorena Michele, Valle Yeminia
Abstract excerpt
INTRODUCTION: Inflammation has gained a pivotal role in the pathophysiology of Acute Coronary Syndrome (ACS). TNF-α is a pro-inflammatory cytokine that could be a potential biomarker in ACS due to its multiple functions. The rs1799964 TNFA polymorphism (-1031T>C) has been associated with a decrease in gene transcription and cytokine levels. OBJECTIVE: To determine the association of rs1799964 TNFA polymorphism...
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