Article
Polymorphism in the MHC2TA gene is associated with features of the metabolic syndrome and cardiovascular mortality.
PloS one - 20 Dec 2006
Lindholm Eero, Melander Olle, Almgren Peter, Berglund Göran, Agardh Carl-David, Groop Leif, Orho-Melander Marju
Abstract excerpt
BACKGROUND: Recently, a -168A-->G polymorphism in the MHC class II transactivator gene (MHC2TA) was shown to be associated with increased susceptibility to myocardial infarction (MI). AIM: To confirm the association between the MHC2TA -168A-->G polymorphism and MI and to study its putative role for microalbuminuria, the metabolic syndrome (MetS) and cardiovascular mortality. MATERIALS AND METHODS: Using an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.