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Article

An intron SNP rs666088 in SLIT2 increases the risk of acute coronary syndrome in an Iranian population.

BMC medical genomics - 14 Oct 2025

Pakdaman Pooria, Naderi Nadereh, Farshidi Narges, Farshidi Hossein, Jafari Zahra, Rahimzadeh Mahsa

Abstract excerpt

BACKGROUND: The Slit guidance Ligand 2 (SLIT2) glycoprotein is of particular interest because of its role in modulating inflammation and the progression of diseases such as atherosclerosis. This study aimed to determine whether SLIT2 polymorphisms can serve as predictive markers for coronary artery disease (CAD) development by investigating its single-nucleotide polymorphisms (SNPs). METHODS: In this case-control...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41088236
DOI: 10.1186/s12920-025-02224-2
PMCID: PMC12522833

Genes

SLIT2
CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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