Novel 6p21.3 Risk Haplotype Predisposes to Acute Coronary Syndrome.

doi:10.1161/CIRCGENETICS.115.001226

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Novel 6p21.3 Risk Haplotype Predisposes to Acute Coronary Syndrome.

Circulation. Cardiovascular genetics - 1 Feb 2016

Sinisalo Juha, Vlachopoulou Efthymia, Marchesani Marja, Nokelainen Johanna, Mäyränpää Mikko I, Lappalainen Jani, Paakkanen Riitta, Wennerström Annika, Salli Krista, Niemi Heikki J, Männistö Satu, Salo Perttu, Junttila Juhani, Eskola Markku, Nikus Kjell, Arstila T Petteri, Perola Markus, Huikuri Heikki, Karhunen Pekka J, Kovanen Petri T, Palotie Aarno, Havulinna Aki S, Lluis-Ganella Carla, Marrugat Jaume, Elosua Roberto, Salomaa Veikko, Nieminen Markku S, Lokki Marja-Liisa

Abstract excerpt

BACKGROUND: The HLA-DRB1*01 allele of the human leukocyte antigen has been associated with acute coronary syndrome. Genome-wide association studies have revealed associations with human leukocyte antigen and non-human leukocyte antigen genes of 3 major histocompatibility complex gene classes but not at allelic level. METHODS AND RESULTS: We conducted a large-scale genetic analysis on a case-control cohort...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Coronary Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Butyrophilins

Share to Coronary Vessels

Share to HLA-DRB1 Chains

Share to Macrophages

Share to Membrane Glycoproteins

Share to Plaque, Atherosclerotic

Share to Th2 Cells

Source

Open in PubMed

Identifiers

PMID: 26679868
DOI: 10.1161/CIRCGENETICS.115.001226

Genes

BTNL2
FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel 6p21.3 Risk Haplotype Predisposes to Acute Coronary Syndrome.PMID 26679868Read ↗

Risk Haplotype of BTNL2 Predisposes Male Patients to NSTEMI: A Genetic and Functional StudySemantic proximity Read ↗

Genetic and immunological insights into COVID-19 with acute myocardial infarction: integrated analysis of mendelian randomization, transcriptomics, and clinical samplesSemantic proximity Read ↗

The MHC2TA 1614 C>G gene polymorphism is associated with risk of developing acute coronary syndrome.Semantic proximity Read ↗

Genome-wide association study of cardiac troponin I in the general population.Semantic proximity Read ↗

Genome-Wide Association and Functional Studies Identify SCML4 and THSD7A as Novel Susceptibility Genes for Coronary Artery Disease.Semantic proximity Read ↗

Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk.Semantic proximity Read ↗

The rs3024839 and rs2227483 polymorphisms with immune pathomechanism offers a starting point for diagnosis and susceptibility testing of myocardial infarction.Semantic proximity Read ↗

Identification of TFEB gene genetic variants in acute myocardial infarctionSemantic proximity Read ↗

The chromosome 9p21.3 coronary heart disease risk allele is associated with altered gene expression in normal heart and vascular tissues.Semantic proximity Read ↗

Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.Semantic proximity Read ↗

TRIB1 and TRPS1 Gene Polymorphisms Are Associated with the Incidence of Acute Coronary Syndrome and Plasma Lipid ConcentrationsSemantic proximity Read ↗

Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.