Article
The interleukin 6 -572 G>C (rs1800796) polymorphism is associated with the risk of developing acute coronary syndrome.
Genetic testing and molecular biomarkers - 1 Dec 2010
Fragoso José Manuel, Delgadillo Hilda, Juárez-Cedillo Teresa, Rodríguez-Pérez José Manuel, Vallejo Maite, Pérez-Méndez Oscar, Alvarez-León Edith, Peña-Duque Marco Antonio, Martínez-Ríos Marco Antonio, Vargas-Alarcón Gilberto
Abstract excerpt
BACKGROUND: inflammation plays an essential role in the development and progression of atherosclerotic lesions and plaque disruption. Cytokines are central regulators in immunoinflammatory mechanisms. The aim of the present study was to evaluate the role of INF-γ and IL-6 gene polymorphisms as susceptibility markers for acute coronary syndromes (ACS) in a group of Mexican patients. METHODS: four polymorphisms...
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