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The T29C polymorphism of the transforming growth factor-β1 (TGF-β1) gene is associated with genetic susceptibility to acute coronary syndrome in Mexican patients.

Cytokine - 1 Jun 2012

Fragoso José Manuel, Martínez-Ríos Marco Antonio, Alvarez-León Edith, Vallejo Maite, Peña-Duque Marco Antonio, Posadas-Sánchez Rosalinda, Posadas-Romero Carlos, Furuzawa-Carballeda Janette, Lima Guadalupe, Llorente Luis, Vargas-Alarcón Gilberto

Abstract excerpt

Inflammation plays an essential role in the development and progression of atherosclerotic lesions, and plaque disruption. The TGF-β1 plays an important role in the anti-inflammatory process. The aim of the present study was to evaluate the role of TGF-β1 gene polymorphisms as susceptibility markers for acute coronary syndrome (ACS). Two polymorphisms (TGF-β -509T>C and TGF-β T29C) of the TGF-β gene were analyzed...

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Identifiers

PMID: 22465044
DOI: 10.1016/j.cyto.2012.03.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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