Article
The MHC2TA 1614 C>G gene polymorphism is associated with risk of developing acute coronary syndrome.
Molecular immunology - 1 Oct 2013
Vargas-Alarcón Gilberto, Martínez-Ríos Marco Antonio, Peña-Duque Marco Antonio, Posadas-Romero Carlos, Cardoso-Saldaña Guillermo, Vallejo Maite, Ramírez-Bello Julián, Pérez-Méndez Oscar, Fragoso José Manuel
Abstract excerpt
BACKGROUND: Inflammation plays an essential role in the development and progression of atherosclerotic lesions. The major histocompatibility complex class II trans-activator (MHC2TA) is considered an important molecule in the inflammatory process regulation. The aim of the present study was to evaluate the role of MHC2TA gene polymorphisms as susceptibility markers for acute coronary syndrome (ACS). METHODS:...
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