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Toll-like receptor 4 gene polymorphisms and acute coronary syndrome: no association in a Mexican population.

Archivos de cardiologia de Mexico - 1 Jan 2000

Martínez-Ríos Marco A, Vargas-Alarcón Gilberto, Vallejo Maite, Cruz-Martínez Erick, Pérez-Méndez Oscar, Medina-Andrade Ángel, De la Torre-García Mónica, Peña-Duque Marco A, Fragoso José Manuel

Abstract excerpt

OBJECTIVE: The objective of this study was to establish the role of the TLR-4 gene polymorphisms in individuals in risk of developing ACS. METHODS: The study included 457 Mexican patients with ACS and 283 control individuals. The TLR-4 Asp299Gly and TLR-4 Thr399Ile single nucleotide polymorphisms were genotyped using 5' exonuclease TaqMan genotyping assays on an 7900HT Fast real-time PCR system according to...

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PMID: 24239012
DOI: 10.1016/j.acmx.2013.09.001

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