Article
MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development.
Neuron - 3 Dec 2014
Ultanir Sila K, Yadav Smita, Hertz Nicholas T, Oses-Prieto Juan A, Claxton Suzanne, Burlingame Alma L, Shokat Kevan M, Jan Lily Y, Jan Yuh-Nung
Abstract excerpt
Mammalian Sterile 20 (Ste20)-like kinase 3 (MST3) is a ubiquitously expressed kinase capable of enhancing axon outgrowth. Whether and how MST3 kinase signaling might regulate development of dendritic filopodia and spine synapses is unknown. Through shRNA-mediated depletion of MST3 and kinase-dead...
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