Article
Conserved Tao Kinase Activity Regulates Dendritic Arborization, Cytoskeletal Dynamics, and Sensory Function in Drosophila.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 26 Feb 2020
Hu Chun, Kanellopoulos Alexandros K, Richter Melanie, Petersen Meike, Konietzny Anja, Tenedini Federico M, Hoyer Nina, Cheng Lin, Poon Carole L C, Harvey Kieran F, Windhorst Sabine, Parrish Jay Z, Mikhaylova Marina, Bagni Claudia, Calderon de Anda Froylan, Soba Peter
Abstract excerpt
Dendritic arborization is highly regulated and requires tight control of dendritic growth, branching, cytoskeletal dynamics, and ion channel expression to ensure proper function. Abnormal dendritic development can result in altered network connectivity, which has been linked to neurodevelopmental disorders, including autism spectrum disorders (ASDs). How neuronal growth control programs tune dendritic...
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