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Article

The Ste20-like kinase SvkA of Dictyostelium discoideum is essential for late stages of cytokinesis.

Journal of cell science - 15 Dec 2007

Rohlfs Meino, Arasada Rajesh, Batsios Petros, Janzen Julia, Schleicher Michael

Abstract excerpt

The genome of the social amoeba Dictyostelium discoideum encodes approximately 285 kinases, which represents approximately 2.6% of the total genome and suggests a signaling complexity similar to that of yeasts and humans. The behavior of D. discoideum as an amoeba and during development relies heavily on fast rearrangements of the actin cytoskeleton. Here, we describe the knockout phenotype of the svkA gene...

Topics

Animals
Cell Division
Cell Polarity
Centrosome
Cytokinesis
Dictyostelium
Genes, Protozoan
Phenotype
Protein Serine-Threonine Kinases
Protozoan Proteins
Recombinant Fusion Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18042625
DOI: 10.1242/jcs.012179

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