Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion of a kinesin I motor unmasks a mechanism of homeostatic branching control by neurotrophin-3.

eLife - 15 Jun 2015

Auer Thomas O, Xiao Tong, Bercier Valerie, Gebhardt Christoph, Duroure Karine, Concordet Jean-Paul, Wyart Claire, Suster Maximiliano, Kawakami Koichi, Wittbrodt Joachim, Baier Herwig, Del Bene Filippo

Abstract excerpt

Development and function of highly polarized cells such as neurons depend on microtubule-associated intracellular transport, but little is known about contributions of specific molecular motors to the establishment of synaptic connections. In this study, we investigated the function of the Kinesin I heavy chain Kif5aa during retinotectal circuit formation in zebrafish. Targeted disruption of Kif5aa does not...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Microscopy, Electron, Transmission
Share to Axons

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Polarity

Share to Kinesins

Share to Neurogenesis

Share to Neurotrophin 3

Share to Time-Lapse Imaging

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 26076409
DOI: 10.7554/eLife.05061
PMCID: PMC4467164

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion of a kinesin I motor unmasks a mechanism of homeostatic branching control by neurotrophin-3.PMID 26076409Read ↗

Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides.Semantic proximity Read ↗

KBP is essential for axonal structure, outgrowth and maintenance in zebrafish, providing insight into the cellular basis of Goldberg-Shprintzen syndrome.Semantic proximity Read ↗

CRMP/UNC-33 organizes microtubule bundles for KIF5-mediated mitochondrial distribution to axon.Semantic proximity Read ↗

Analysis of IFT kinesins in developing zebrafish cone photoreceptor sensory cilia.Semantic proximity Read ↗

Plexin A3 and turnout regulate motor axonal branch morphogenesis in zebrafish.Semantic proximity Read ↗

Mutation of Kinesin-6 Kif20b causes defects in cortical neuron polarization and morphogenesis.Semantic proximity Read ↗

Dynamic microtubules drive circuit rewiring in the absence of neurite remodeling.Semantic proximity Read ↗

A systems-level proteomic analysis identifies kinesin targets of KIFBP during neuronal developmentSemantic proximity Read ↗

Intellectual disability-causing mutations in KIF11 impair microtubule dynamics and dendritic arborization.Semantic proximity Read ↗

Analysis of kinesin-2 function in photoreceptor cells using synchronous Cre-loxP knockout of Kif3a with RHO-Cre.Semantic proximity Read ↗

Constitutively active myosin light chain kinase alters axon guidance decisions in Drosophila embryos.Semantic proximity Read ↗

Whole-mount imaging of mouse embryo sensory axon projections.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.