Article
Doublecortin-like kinase enhances dendritic remodelling and negatively regulates synapse maturation.
Nature communications - 1 Jan 2013
Shin Euikyung, Kashiwagi Yutaro, Kuriu Toshihiko, Iwasaki Hirohide, Tanaka Teruyuki, Koizumi Hiroyuki, Gleeson Joseph G, Okabe Shigeo
Abstract excerpt
Dendritic morphogenesis and formation of synapses at appropriate dendritic locations are essential for the establishment of proper neuronal connectivity. Recent imaging studies provide evidence for stabilization of dynamic distal branches of dendrites by the addition of new synapses. However, molecules involved in both dendritic growth and suppression of synapse maturation remain to be identified. Here we report...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
