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Article

A Myosin Va mutant mouse with disruptions in glutamate synaptic development and mature plasticity in visual cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 8 May 2013

Yoshii Akira, Zhao Jian-Ping, Pandian Swarna, van Zundert Brigitte, Constantine-Paton Martha

Abstract excerpt

Myosin Va (MyoVa) mediates F-actin-based vesicular transport toward the plasma membrane and is found at neuronal postsynaptic densities (PSDs), but the role of MyoVa in synaptic development and function is largely unknown. Here, in studies using the dominant-negative MyoVa neurological mutant mouse Flailer, we find that MyoVa plays an essential role in activity-dependent delivery of PSD-95 and other critical PSD...

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Source

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Identifiers

PMID: 23658184
DOI: 10.1523/JNEUROSCI.4585-12.2013
PMCID: PMC3699337

Genes

PSD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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