Article
Maternal diet during gestation and lactation modifies the severity of salt-induced hypertension and renal injury in Dahl salt-sensitive rats.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2015
Geurts Aron M, Mattson David L, Liu Pengyuan, Cabacungan Erwin, Skelton Meredith M, Kurth Theresa M, Yang Chun, Endres Bradley T, Klotz Jason, Liang Mingyu, Cowley Allen W
Abstract excerpt
Environmental exposure of parents or early in life may affect disease development in adults. We found that hypertension and renal injury induced by a high-salt diet were substantially attenuated in Dahl SS/JrHsdMcwiCrl (SS/Crl) rats that had been maintained for many generations on the grain-based 5L2F diet compared with SS/JrHsdMcwi rats (SS/Mcw) maintained on the casein-based AIN-76A diet (mean arterial...
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